Am J Psychiatry 1990; 147:796-797
Copyright © 1990 by American Psychiatric Association
Response to 35% CO2 as a marker of panic in severe anxiety
E Griez, J Zandbergen, H Pols and C de Loof
Academic Anxiety Center, Mental Hospital Vijverdal, The Netherlands.
One inhalation of 35% CO2 was administered to each of 32 patients with high
anxiety ratings. Only patients with panic disorder had increases in
reported anxiety upon CO2 intake. CO2-triggered anxiety appears specific
for panic disorder and independent of baseline anxiety.
