Am J Psychiatry 1990; 147:740-745
Copyright © 1990 by American Psychiatric Association
Eye tracking impairment in clinically identified patients with schizotypal personality disorder
LJ Siever, R Keefe, DP Bernstein, EF Coccaro, HM Klar, Z Zemishlany, AE Peterson, M Davidson, T Mahon and T Horvath
Department of Psychiatry, Mt. Sinai School of Medicine, Bronx, N.Y.
Eye tracking accuracy, which has been found to be impaired in schizophrenic
patients and their relatives, was assessed in 26 patients with schizotypal
personality disorder, 17 control subjects with other
non-schizophrenia-related personality disorders, 29 normal control
subjects, and 44 schizophrenic patients. Both schizotypal and schizophrenic
patients, but not control subjects with other personality disorders,
demonstrated significantly more impaired tracking than the normal control
subjects. These results suggest that patients with clinically defined
schizotypal personality disorder may be biologically related to
schizophrenic patients as part of a spectrum of schizophrenia-related
disorders.
