Am J Psychiatry 1990; 147:495-497
Copyright © 1990 by American Psychiatric Association
Effect of imipramine on depression and immune status in a sample of men with HIV infection
JG Rabkin and WM Harrison
New York State Psychiatric Institute, NY 10032.
Eleven men with major depression and human immunodeficiency virus (HIV)
infection underwent an open trial of imipramine. Eight of nine (89%) who
completed 12 weeks responded. The mean decline in T4 cells from baseline
was 100 at week 12 and 16 at week 26. No major exacerbations of HIV
infection occurred.