Am J Psychiatry 1990; 147:477-480
Copyright © 1990 by American Psychiatric Association
Glucose tolerance testing in women with premenstrual syndrome
KD Denicoff, C Hoban, GN Grover and DR Rubinow
Biological Psychiatry Branch, NIMH, Bethesda, MD 20892.
Glucose tolerance tests (GTTs) were administered to 11 women with
premenstrual syndrome (PMS) to ascertain whether the patients had
abnormalities of glucose tolerance, to determine whether such abnormalities
were related to menstrual cycle phase, and to compare the symptoms during
the GTT with the PMS symptoms experienced in the luteal phase. Two GTTs
were performed for each patient, one during the late follicular phase and
one during the late luteal phase. Although many patients experienced
symptoms of hypoglycemia during the GTT, the hypoglycemia symptoms were not
specific to the luteal phase and did not resemble the patients' PMS
symptoms.
