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Am J Psychiatry 1990; 147:239-242
Copyright © 1990 by American Psychiatric Association


REGULAR ARTICLES

Treatment of Alzheimer's disease with short- and long-term oral THA and lecithin: a double-blind study

LJ Fitten, KM Perryman, PL Gross, H Fine, J Cummins and C Marshall
VA Medical Center, Sepulveda, Calif 91343.

Ten Alzheimer's disease patients underwent a trial of oral tetrahydroaminoacridine (THA) and lecithin. After 3 inpatient weeks there was no clear therapeutic effect. Three of six patients able to continue in long-term treatment showed measurable cognitive improvement, but only one displayed clinically obvious improvement.


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