Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease



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Am J Psychiatry 1990; 147:1656-1661
Copyright © 1990 by American Psychiatric Association

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Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease

EA Walker, PP Roy-Byrne, WJ Katon, L Li, D Amos and G Jiranek
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle 98195.

Structured psychiatric interviews and psychological self-report measures were administered to 28 patients with irritable bowel syndrome and 19 patients with inflammatory bowel disease. Significantly more of the patients with irritable bowel syndrome had lifetime diagnoses of major depression, somatization disorder, generalized anxiety disorder, panic disorder, and phobic disorder. They had significantly more medically unexplained somatic symptoms, and most had suffered from psychiatric disorders, particularly anxiety disorders, before the onset of their irritable bowel symptoms.

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