Am J Psychiatry 1989; 146:911-913
Copyright © 1989 by American Psychiatric Association
Elevated antidepressant plasma levels after addition of fluoxetine
AB Aranow, JI Hudson, HG Pope Jr, TA Grady, TA Laage, IR Bell and JO Cole
Laboratories for Psychiatric Research, McLean Hospital, Belmont, MA 02178.
Four patients treated with tricyclic antidepressants and one patient
treated with trazodone all demonstrated marked increases in plasma levels
of these drugs after the addition of fluoxetine. Such increases could
increase adverse effects.
