Am J Psychiatry 1989; 146:1423-1426
Copyright © 1989 by American Psychiatric Association
Use of medication and in vivo exposure in volunteers for panic disorder research
CB Taylor, R King, J Margraf, A Ehlers, M Telch, WT Roth and WS Agras
Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305-5490.
A survey of 794 subjects volunteering for studies of panic disorder with or
without phobic avoidance revealed that fewer than 15% had received
imipramine and fewer than 15% had undergone in vivo exposure, although the
majority had engaged in some form of counseling and had used
benzodiazepines. Subjects with spontaneous panic attacks reported more
avoidance than subjects with situational attacks. One-half of the subjects
were unemployed. The authors recommend wider use of the available effective
treatments for panic disorder and phobic avoidance.