Am J Psychiatry 1988; 145:1012-1014
Copyright © 1988 by American Psychiatric Association
Occult thyroid dysfunction in patients with refractory depression
GR Gewirtz, D Malaspina, JA Hatterer, S Feureisen, D Klein and JM Gorman
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY.
Assessment of metabolic rate was useful in evaluating refractory depression
in six of 15 women. Five of the six had normal levels of T3 and T4;
however, each had an elevated thyrotropin-stimulating hormone level or a
low metabolic rate. The depressions responded to medication with thyroid
hormone.
