Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications



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Am J Psychiatry 1988; 145:742-744
Copyright © 1988 by American Psychiatric Association

REGULAR ARTICLES

Adjunctive alprazolam for schizophrenia with panic anxiety: clinical observation and pathogenetic implications

JP Kahn, MA Puertollano, MD Schane and DF Klein
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032.

Seven patients with schizophrenia and panic attacks all showed marked improvement of positive and negative schizophrenic symptoms when alprazolam was openly added to antipsychotic medication. Panic attacks may identify alprazolam-responsive schizophrenic patients and may define a distinct pathophysiologic subgroup.

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