Am J Psychiatry 1988; 145:517-518
Copyright © 1988 by American Psychiatric Association

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A prospective survey of neuroleptic malignant syndrome in a short-term psychiatric hospital

AJ Gelenberg, B Bellinghausen, JD Wojcik, WE Falk and GS Sachs
Department of Psychiatry, Massachusetts General Hospital, Boston.

Of 1,470 patients treated with neuroleptics during 1 year at a private psychiatric hospital, only one patient developed neuroleptic malignant syndrome--an annual frequency of 0.07%. Use of low doses of neuroleptics may account for this frequency, which is below recent estimates.

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