Am J Psychiatry 1988; 145:251-253
Copyright © 1988 by American Psychiatric Association
Low frontal glucose utilization in chronic schizophrenia: a replication study
A Wolkin, B Angrist, A Wolf, JD Brodie, B Wolkin, J Jaeger, R Cancro and J Rotrosen
Department of Psychiatry, New York University School of Medicine, New York City.
Frontal/posterior ratios of cerebral glucose metabolism as determined by
positron emission tomography were significantly lower in 13 chronic
schizophrenic patients than in eight normal control subjects, as were
absolute metabolic rates in both the frontal and posterior regions. The
differences were not accounted for by cerebral atrophy.
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