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Am J Psychiatry 1988; 145:1564-1567
Copyright © 1988 by American Psychiatric Association


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Prodromal symptoms in panic disorder with agoraphobia

GA Fava, S Grandi and R Canestrari
Department of Psychology, University of Bologna, Italy.

Of 20 patients suffering from panic disorder with agoraphobia, 18 reported experiencing agoraphobic avoidance, generalized anxiety, and/or hypochondriacal fears and beliefs before the first panic attack. The prevalence of these symptoms in the patients was significantly higher than the prevalence in 20 healthy control subjects. The results indicate that phobic avoidance in panic disorder with agoraphobia may not be secondary to the panic attacks, a finding that runs counter to the current DSM-III-R classification of anxiety disorders.


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