Am J Psychiatry 1988; 145:1455-1456
Copyright © 1988 by American Psychiatric Association

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Higher frequency of neuroleptic-induced dystonia in mania than in schizophrenia

HA Nasrallah, CM Churchill and GA Hamdan-Allan
Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210.

In a study of 135 schizophrenic and 46 manic male patients treated with neuroleptics, a significantly higher proportion of the manic patients (26.1%) than of the schizophrenic patients (5.9%) developed acute dystonia. This suggests a higher vulnerability to acute extrapyramidal symptoms in mania.

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