Am J Psychiatry 1988; 145:1384-1390
Copyright © 1988 by American Psychiatric Association
Cerebral blood flow during delirium tremens and related clinical states studied with xenon-133 inhalation tomography
R Hemmingsen, S Vorstrup, L Clemmesen, S Holm, P Tfelt-Hansen, AS Sorensen, C Hansen, W Sommer and TG Bolwig
Department of Psychiatry, Copenhagen University Hospital, Denmark.
The regional cerebral blood flow of 12 patients with severe alcohol
withdrawal reactions (delirium tremens or impending delirium tremens) was
measured during the acute state before treatment and after recovery.
Greater cerebral blood flow was significantly correlated with visual
hallucinations and agitation during the acute withdrawal reaction. The
results suggest that delirium tremens and related clinical states represent
a type of acute brain syndrome mainly characterized by CNS
hyperexcitability.