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Am J Psychiatry 1988; 145:1384-1390
Copyright © 1988 by American Psychiatric Association


REGULAR ARTICLES

Cerebral blood flow during delirium tremens and related clinical states studied with xenon-133 inhalation tomography

R Hemmingsen, S Vorstrup, L Clemmesen, S Holm, P Tfelt-Hansen, AS Sorensen, C Hansen, W Sommer and TG Bolwig
Department of Psychiatry, Copenhagen University Hospital, Denmark.

The regional cerebral blood flow of 12 patients with severe alcohol withdrawal reactions (delirium tremens or impending delirium tremens) was measured during the acute state before treatment and after recovery. Greater cerebral blood flow was significantly correlated with visual hallucinations and agitation during the acute withdrawal reaction. The results suggest that delirium tremens and related clinical states represent a type of acute brain syndrome mainly characterized by CNS hyperexcitability.


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