
Am J Psychiatry 1987; 144:1148-1153
Copyright © 1987 by American Psychiatric Association
Clinical nonrecognition of neuroleptic-induced movement disorders: a cautionary study
PJ Weiden, JJ Mann, G Haas, M Mattson and A Frances
Extrapyramidal side effects are a major limitation in the use of
neuroleptics, and tardive dyskinesia is a special public health problem.
Accurate clinical diagnosis of extrapyramidal syndromes is necessary for
effective management. The authors compared clinicians' recognition of the
major extrapyramidal syndromes in 48 psychotic inpatients with independent
blind diagnoses by clinical researchers using standardized ratings. The
major finding was a high rate of clinical underrecognition of all major
extrapyramidal syndromes, especially tardive dyskinesia. The authors
discuss the clinical predictors of nonrecognition of extrapyramidal side
effects and recommend improved training in their detection.
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