Am J Psychiatry 1987; 144:1084-1085
Copyright © 1987 by American Psychiatric Association
Absence of acquired tolerance to neuroleptics in schizophrenic patients
T Palmstierna and B Wistedt
Development of increased tolerance to neuroleptics was investigated in 38
neuroleptic-respondent schizophrenic patients. At 5- or 8-year follow-up,
clinical global assessments were related to changes in neuroleptic doses.
In 93% of the patients gradually increasing tolerance could be excluded.