Am J Psychiatry 1987; 144:889-895
Copyright © 1987 by American Psychiatric Association
Characteristics of very poor outcome schizophrenia
RS Keefe, RC Mohs, MF Losonczy, M Davidson, JM Silverman, KS Kendler, TB Horvath, R Nora and KL Davis
The authors compared 21 "Kraepelinian" schizophrenic patients who had been
ill and dependent on others for the past 5 years with 76 chronic
schizophrenic patients in remission or with exacerbations requiring
hospitalization. The Kraepelinian patients met the criteria for
schizophrenia by more diagnostic systems than the exacerbated patients,
were less responsive to haloperidol, had more severe negative symptoms, and
had similarly severe positive symptoms. They had cerebral ventricles that
were more asymmetrical and a greater family history of schizophrenia
spectrum disorders than the other chronic patients. These data suggest that
patients with 5 years of illness and complete dependency on others may
represent a subgroup of schizophrenia.
This article has been cited by other articles:
|
|
|
|
 
B. F. O'Donnell
Cognitive Impairment in Schizophrenia: A Life Span Perspective
American Journal of Alzheimer's Disease and Other Dementias,
November 1, 2007;
22(5):
398 - 405.
[Abstract]
[PDF]
|
|
|
|
|
|
|
A. M. Brickman, M. S. Buchsbaum, Z. Ivanov, J. C. Borod, N. S. Foldi, E. Hahn, S. A. Mitelman, E. A. Hazlett, S. J. Lincoln, R. E. Newmark, et al.
Internal Capsule Size in Good-Outcome and Poor-Outcome Schizophrenia
J Neuropsychiatry Clin Neurosci,
August 1, 2006;
18(3):
364 - 376.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
P. D Harvey, D. Koren, A. Reichenberg, and C. R Bowie
Negative Symptoms and Cognitive Deficits: What Is the Nature of Their Relationship?
Schizophr Bull,
April 1, 2006;
32(2):
250 - 258.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
B.-C. Ho, P. Nopoulos, M. Flaum, S. Arndt, and N. C. Andreasen
Two-Year Outcome in First-Episode Schizophrenia: Predictive Value of Symptoms for Quality of Life
Focus,
January 1, 2004;
2(1):
131 - 137.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. A. Mitelman, L. Shihabuddin, A. M. Brickman, E. A. Hazlett, and M. S. Buchsbaum
MRI Assessment of Gray and White Matter Distribution in Brodmann's Areas of the Cortex in Patients With Schizophrenia With Good and Poor Outcomes
Am J Psychiatry,
December 1, 2003;
160(12):
2154 - 2168.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
L. Rioux, J. Nissanov, K. Lauber, W. B. Bilker, and S. E. Arnold
Distribution of Microtubule-Associated Protein MAP2-Immunoreactive Interstitial Neurons in the Parahippocampal White Matter in Subjects With Schizophrenia
Am J Psychiatry,
January 1, 2003;
160(1):
149 - 155.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. Malaspina, R. R. Goetz, S. Yale, A. Berman, J. H. Friedman, F. Tremeau, D. Printz, X. Amador, J. Johnson, A. Brown, et al.
Relation of Familial Schizophrenia to Negative Symptoms But Not to the Deficit Syndrome
Am J Psychiatry,
June 1, 2000;
157(6):
994 - 1003.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
M. E. Kelley, D. P. van Kammen, and D. N. Allen
Empirical Validation of Primary Negative Symptoms: Independence From Effects of Medication and Psychosis
Am J Psychiatry,
March 1, 1999;
156(3):
406 - 411.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
B.-C. Ho, P. Nopoulos, M. Flaum, S. Arndt, and N. C. Andreasen
Two-Year Outcome in First-Episode Schizophrenia: Predictive Value of Symptoms for Quality of Life
Am J Psychiatry,
September 1, 1998;
155(9):
1196 - 1201.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
G. Goldstein, D. N. Allen, and D. P. van Kammen
Individual Differences in Cognitive Decline in Schizophrenia
Am J Psychiatry,
August 1, 1998;
155(8):
1117 - 1118.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
R. Michels and P. M. Marzuk
Progress in Psychiatry- First of Two Parts
N. Engl. J. Med.,
August 19, 1993;
329(8):
552 - 560.
[Full Text]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1987
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
