ECG changes during haloperidol and pimozide treatment of Tourette's disorder



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Am J Psychiatry 1987; 144:673-675
Copyright © 1987 by American Psychiatric Association

BRIEF REPORTS

ECG changes during haloperidol and pimozide treatment of Tourette's disorder

G Fulop, RA Phillips, AK Shapiro, JA Gomes, E Shapiro and JW Nordlie

The ECG QTc interval was significantly prolonged by pimozide but not haloperidol or placebo in a randomized clinical trial with 40 patients with Tourette's disorder. However, no adverse cardiac effects or differences in rate, rhythm, or waveform were found.

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