Am J Psychiatry 1987; 144:1480-1483
Copyright © 1987 by American Psychiatric Association
Platelet MAO activity in geriatric patients with depression and dementia
GS Alexopoulos, RC Young, KW Lieberman and CA Shamoian
Department of Psychiatry, New York Hospital-Cornell Medical Center, Cornell University Medical College, White Plains 10605.
The authors studied platelet MAO activity in psychiatrically hospitalized
geriatric patients with depression and dementia. Platelet MAO activity was
higher in demented patients with and without depression and in depressed
patients with reversible dementia than in nondemented depressed patients.
The data suggest that abnormally high platelet MAO activity may reflect a
predisposition to the development of a dementia syndrome.
