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Am J Psychiatry 1987; 144:41-45
Copyright © 1987 by American Psychiatric Association
Frequency and presentation of depressive symptoms in patients with primary degenerative dementia [published erratum appears in Am J Psychiatry 1987 Apr;144(4):542]
LW Lazarus, N Newton, B Cohler, J Lesser and C Schweon
The authors examined the frequency and severity of depressive symptoms in
elderly patients with presumed primary degenerative dementia and identified
the signs and symptoms that provide a reliable basis for diagnosing
depression. Forty-four patients and 42 control subjects were interviewed
and rated on the Hamilton Rating Scale for Depression and the Sandoz
Clinical Assessment-Geriatric Scale. Nine of the patients demonstrated
symptoms suggestive of mild, four of moderate, and five of severe
depression. Patients had significantly higher scores than control subjects
on items that assess intrapsychic rather than vegetative symptoms of
depression. These findings underline the importance of maintaining a high
index of suspicion for concomitant depressive symptoms in patients with
primary degenerative dementia.
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