Am J Psychiatry 1986; 143:1155-1158
Copyright © 1986 by American Psychiatric Association
Outcome study of first-episode psychosis. I: Relapse rates after 1 year
CJ Rabiner, JT Wegner and JM Kane
One-year relapse rates were assessed in a group of 64 patients diagnosed by
Research Diagnostic Criteria who were hospitalized for their first
psychotic episode. Life-table analysis showed that of the 51 remitted
patients, 71.4% of the schizophrenic patients (N = 20), 71.4% of patients
with affective disorders (N = 10), and 77.8% of patients diagnosed as
having either unspecified functional psychosis or other psychiatric
disorder (N = 7) remained in remission at 1-year follow-up. Factors
associated with relapse or poor outcome (patients who remained in episode)
included no maintenance medication, longer duration of illness, and
premorbid asociality.