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Am J Psychiatry 1986; 143:1113-1118
Copyright © 1986 by American Psychiatric Association

REGULAR ARTICLES

Correlates of lateral ventricular size in chronic schizophrenia, II: biological measures

MF Losonczy, IS Song, RC Mohs, AA Mathe, M Davidson, BM Davis and KL Davis

CSF homovanillic acid levels showed a significant negative correlation with ventricle-brain ratios (VBRs) in a group of drug-free chronic schizophrenic male veterans, while CSF 5-hydroxyindoleacetic acid levels showed a similar, nearly significant trend. The response of plasma human growth hormone to 0.75 mg of apomorphine also demonstrated a significant negative correlation with VBR in this group, but other measures of central neurotransmitter activity were unrelated to ventricular size.




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