Am J Psychiatry 1986; 143:919-921
Copyright © 1986 by American Psychiatric Association
Physostigmine-induced epinephrine release in patients with affective disorder
DS Janowsky, SC Risch, MG Ziegler, JC Gillin, L Huey and J Rausch
Infusion of the cholinomimetic drug physostigmine led to profound increases
in serum epinephrine levels and slight increases in serum norepinephrine
levels among 38 patients with affective disorder and 22 control subjects.
Preliminary results suggest that physostigmine may induce relatively
blunted increases in serum epinephrine levels in patients with affective
disorders.
