Am J Psychiatry 1986; 143:530-532
Copyright © 1986 by American Psychiatric Association
Concomitant obsessive-compulsive disorder and schizotypal personality disorder
MA Jenike, L Baer, WE Minichiello, CE Schwartz and RJ Carey Jr
Despite advances in the management of patients with obsessive- compulsive
disorder, some remain refractory to treatment. The authors retrospectively
examined characteristics of 43 treatment-resistant obsessive-compulsive
patients and found that those with concomitant schizotypal personality
disorder had an extremely high rate of treatment failure. Of the 29 treated
nonschizotypal patients, 26 (90%) improved at least moderately; only one of
14 (7%) schizotypal patients improved. In addition, the number of
schizotypal features in each patient was strongly negatively correlated
with treatment outcome.
