Am J Psychiatry 1986; 143:519-522
Copyright © 1986 by American Psychiatric Association
Positive effects of carbamazepine on behavioral dyscontrol in borderline personality disorder
DL Gardner and RW Cowdry
In a double-blind crossover trial, carbamazepine, an anticonvulsant with
primary effects on subcortical limbic structures, decreased the severity of
behavioral dyscontrol in 11 women with borderline personality disorder
significantly more than placebo. The authors emphasize the preliminary
nature of their findings and discuss alternative hypotheses regarding
mechanisms by which carbamazepine might influence behavioral dyscontrol.
