|
| | |
|
Am J Psychiatry 1986; 143:300-305
Copyright © 1986 by American Psychiatric Association
Cortisol and Alzheimer's disease, I: Basal studies
KL Davis, BM Davis, BS Greenwald, RC Mohs, AA Mathe, CA Johns and TB Horvath
Patients with Alzheimer's disease and nondemented elderly control subjects
participated in studies of cortisol secretion during sleep and at 9:00 a.m.
and were given dexamethasone suppression tests (DSTs) and lumbar punctures.
Nocturnal and 9:00 a.m. cortisol concentrations were significantly higher
in the demented patients. CSF MHPG negatively correlated with mean
nocturnal cortisol. The most severely demented patients had the highest
9:00 a.m. and mean nocturnal cortisol concentrations. DST results did not
distinguish samples with substantially different nocturnal cortisol
concentrations. These results suggest that measurements of basal plasma
cortisol concentrations and dexamethasone suppression provide different
information but support the notion of somewhat higher than normal cortisol
concentrations in Alzheimer's disease patients.
This article has been cited by other articles:
|
|
|
|
 
S. M MacKenzie, D. Dewar, W. Stewart, R. Fraser, J. M C Connell, and E. Davies
The transcription of steroidogenic genes in the human cerebellum and hippocampus: a comparative survey of normal and Alzheimer's tissue
J. Endocrinol.,
January 1, 2008;
196(1):
123 - 130.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. L. Wright and C. Persad
Distinguishing Between Depression and Dementia in Older Persons: Neuropsychological and Neuropathological Correlates
J Geriatr Psychiatry Neurol,
December 1, 2007;
20(4):
189 - 198.
[Abstract]
[PDF]
|
|
|
|
|
|
|
B. K. Lee, T. A. Glass, M. J. McAtee, G. S. Wand, K. Bandeen-Roche, K. I. Bolla, and B. S. Schwartz
Associations of Salivary Cortisol With Cognitive Function in the Baltimore Memory Study
Arch Gen Psychiatry,
July 1, 2007;
64(7):
810 - 818.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
J. G. Csernansky, H. Dong, A. M. Fagan, L. Wang, C. Xiong, D. M. Holtzman, and J. C. Morris
Plasma Cortisol and Progression of Dementia in Subjects With Alzheimer-Type Dementia
Am J Psychiatry,
December 1, 2006;
163(12):
2164 - 2169.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
K. N. Green, L. M. Billings, B. Roozendaal, J. L. McGaugh, and F. M. LaFerla
Glucocorticoids Increase Amyloid-beta and Tau Pathology in a Mouse Model of Alzheimer's Disease.
J. Neurosci.,
August 30, 2006;
26(35):
9047 - 9056.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. J. Morton, N. I. Wood, M. H. Hastings, C. Hurelbrink, R. A. Barker, and E. S. Maywood
Disintegration of the Sleep-Wake Cycle and Circadian Timing in Huntington's Disease
J. Neurosci.,
January 5, 2005;
25(1):
157 - 163.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. J.-F. de Quervain, R. Poirier, M. A. Wollmer, L. M.E. Grimaldi, M. Tsolaki, J. R. Streffer, C. Hock, R. M. Nitsch, M. H. Mohajeri, and A. Papassotiropoulos
Glucocorticoid-related genetic susceptibility for Alzheimer's disease
Hum. Mol. Genet.,
January 1, 2004;
13(1):
47 - 52.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
D. L. Woods and M. Dimond
The Effect of Therapeutic Touch on Agitated Behavior and Cortisol in Persons with Alzheimer's Disease
Biol Res Nurs,
October 1, 2002;
4(2):
104 - 114.
[Abstract]
[PDF]
|
|
|
|
|
|
|
E. R. Peskind, C. W. Wilkinson, E. C. Petrie, G. D. Schellenberg, and M. A. Raskind
Increased CSF cortisol in AD is a function of APOE genotype
Neurology,
April 24, 2001;
56(8):
1094 - 1098.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
A. Kudoh, H. Katagai, and T. Takazawa
Endocrine response to surgical stress in three patients over 100 yr
Can J Anesth,
April 1, 2001;
48(4):
340 - 343.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. J. Cunningham, M. Sinnott, A. Denihan, M. Rowan, J. B. Walsh, R. O’Moore, D. Coakley, R. F. Coen, B. A. Lawler, and D. D. O’Neill
Endogenous Sex Hormone Levels in Postmenopausal Women with Alzheimer's Disease
J. Clin. Endocrinol. Metab.,
March 1, 2001;
86(3):
1099 - 1103.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
J. Raber, S. F. Akana, S. Bhatnagar, M. F. Dallman, D. Wong, and L. Mucke
Hypothalamic-Pituitary-Adrenal Dysfunction in Apoe-/- Mice: Possible Role in Behavioral and Metabolic Alterations
J. Neurosci.,
March 1, 2000;
20(5):
2064 - 2071.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
G. R.J. Swanwick, M. Kirby, I. Bruce, F. Buggy, R. F. Coen, D. Coakley, and B. A. Lawlor
Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Alzheimer's Disease: Lack of Association Between Longitudinal and Cross-Sectional Findings
Am J Psychiatry,
February 1, 1998;
155(2):
286 - 289.
[Abstract]
[Full Text]
|
|
|
|
|
|
|
M. J. de Leon, T. McRae, H. Rusinek, A. Convit, S. De Santi, C. Tarshish, J. Golomb, N. Volkow, K. Daisley, N. Orentreich, et al.
Cortisol Reduces Hippocampal Glucose Metabolism in Normal Elderly, but Not in Alzheimer's Disease
J. Clin. Endocrinol. Metab.,
October 1, 1997;
82(10):
3251 - 3259.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
C. Behl, F. Lezoualc'h, T. Trapp, M. Widmann, T. Skutella, and F. Holsboer
Glucocorticoids Enhance Oxidative Stress-Induced Cell Death in Hippocampal Neurons in Vitro
Endocrinology,
January 1, 1997;
138(1):
101 - 106.
[Abstract]
[Full Text]
[PDF]
|
|
|
|
|
|
|
S. Skare, B. Pew, and M. Dysken
The Dexamethasone Suppression Test in Dementia: A Review of the Literature
J Geriatr Psychiatry Neurol,
July 1, 1990;
3(3):
124 - 138.
[Abstract]
[PDF]
|
|
|
Get information about faster international access.
Privacy Policy
Copyright © 1986
American Psychiatric Association.
All rights reserved.
Home
| Search
| Current Issue
| Past Issues
| Subscribe
| All APPI Journals
| Help
| Contact Us
|
