Reliability of the family history method in genetic studies of Alzheimer's disease and related dementias



	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted
	Citation Map



	Email this article to a Colleague
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Add to My Articles & Searches
	Download to citation manager



	Citing Articles via HighWire
	Citing Articles via Google Scholar



	Articles by Silverman, J. M.
	Articles by Davis, K. L.
	Search for Related Content



	PubMed Citation
	Articles by Silverman, J. M.
	Articles by Davis, K. L.

Am J Psychiatry 1986; 143:1279-1282
Copyright © 1986 by American Psychiatric Association

REGULAR ARTICLES

Reliability of the family history method in genetic studies of Alzheimer's disease and related dementias

JM Silverman, JC Breitner, RC Mohs and KL Davis

The investigation of genetic and other causes of Alzheimer's disease requires reliable and valid methods of gathering historical data on elderly relatives. To assess the reliability of the family history method in the study of late-onset dementing illness, the authors studied families with Alzheimer's disease probands and control families. The results indicated that family history data obtained from multiple informants with standardized instruments are consistent across informants. The rate of Alzheimer's disease in the families studied was similar to rates found in previous studies.

This article has been cited by other articles:

M. M. Mielke, P. B. Rosenberg, J. Tschanz, L. Cook, C. Corcoran, K. M. Hayden, M. Norton, P. V. Rabins, R. C. Green, K. A. Welsh-Bohmer, et al.
Vascular factors predict rate of progression in Alzheimer disease
Neurology, November 6, 2007; 69(19): 1850 - 1858.
[Abstract] [Full Text] [PDF]

W. A. Rocca, J. H. Bower, J. E. Ahlskog, A. Elbaz, B. R. Grossardt, S. K. McDonnell, D. J. Schaid, and D. M. Maraganore
Risk of Cognitive Impairment or Dementia in Relatives of Patients With Parkinson Disease
Arch Neurol, October 1, 2007; 64(10): 1458 - 1464.
[Abstract] [Full Text] [PDF]

W. A. Rocca, J. H. Bower, D. M. Maraganore, J. E. Ahlskog, B. R. Grossardt, M. de Andrade, and L. J. Melton III
Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause
Neurology, September 11, 2007; 69(11): 1074 - 1083.
[Abstract] [Full Text] [PDF]

B. Cullen, B. O'Neill, J. J Evans, R. F Coen, and B. A Lawlor
A review of screening tests for cognitive impairment
J. Neurol. Neurosurg. Psychiatry, August 1, 2007; 78(8): 790 - 799.
[Abstract] [Full Text] [PDF]

ADAPT Research Group
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial
Neurology, May 22, 2007; 68(21): 1800 - 1808.
[Abstract] [Full Text] [PDF]

C. U. Onyike, J.-M. E. Sheppard, J. T. Tschanz, M. C. Norton, R. C. Green, M. Steinberg, K. A. Welsh-Bohmer, J. C. Breitner, and C. G. Lyketsos
Epidemiology of Apathy in Older Adults: The Cache County Study
Am J Geriatr Psychiatry, May 1, 2007; 15(5): 365 - 375.
[Abstract] [Full Text] [PDF]

S. S. Bassett, D. M. Yousem, C. Cristinzio, I. Kusevic, M. A. Yassa, B. S. Caffo, and S. L. Zeger
Familial risk for Alzheimer's disease alters fMRI activation patterns
Brain, May 1, 2006; 129(5): 1229 - 1239.
[Abstract] [Full Text] [PDF]

A. S. Khachaturian, P. P. Zandi, C. G. Lyketsos, K. M. Hayden, I. Skoog, M. C. Norton, J. T. Tschanz, L. S. Mayer, K. A. Welsh-Bohmer, J. C. S. Breitner, et al.
Antihypertensive Medication Use and Incident Alzheimer Disease: The Cache County Study
Arch Neurol, May 1, 2006; 63(5): 686 - 692.
[Abstract] [Full Text] [PDF]

D. C. Steffens, M. Maytan, M. J. Helms, and B. L. Plassman
Prevalence and clinical correlates of neuropsychiatric symptoms in dementia
American Journal of Alzheimer's Disease and Other Dementias, November 1, 2005; 20(6): 367 - 373.
[Abstract] [PDF]

C. G. Lyketsos, L. Toone, J. Tschanz, P. V. Rabins, M. Steinberg, C. U. Onyike, C. Corcoran, M. Norton, P. Zandi, J. C.S. Breitner, et al.
Population-Based Study of Medical Comorbidity in Early Dementia and "Cognitive Impairment, No Dementia (CIND)": Association With Functional and Cognitive Impairment: The Cache County Study
Am J Geriatr Psychiatry, August 1, 2005; 13(8): 656 - 664.
[Abstract] [Full Text] [PDF]

J. M. Silverman, G. Ciresi, C. J. Smith, D. B. Marin, and M. Schnaider-Beeri
Variability of Familial Risk of Alzheimer Disease Across the Late Life Span
Arch Gen Psychiatry, May 1, 2005; 62(5): 565 - 573.
[Abstract] [Full Text] [PDF]

M. Schnaider Beeri, M. Davidson, J. M. Silverman, S. Noy, J. Schmeidler, and U. Goldbourt
Relationship Between Body Height and Dementia
Am J Geriatr Psychiatry, February 1, 2005; 13(2): 116 - 123.
[Abstract] [Full Text] [PDF]

P. P. Zandi, D. L. Sparks, A. S. Khachaturian, J. Tschanz, M. Norton, M. Steinberg, K. A. Welsh-Bohmer, J. C. S. Breitner, and for the Cache County Study Investigators
Do Statins Reduce Risk of Incident Dementia and Alzheimer Disease?: The Cache County Study
Arch Gen Psychiatry, February 1, 2005; 62(2): 217 - 224.
[Abstract] [Full Text] [PDF]

M. Schnaider Beeri, U. Goldbourt, J. M. Silverman, S. Noy, J. Schmeidler, R. Ravona-Springer, A. Sverdlick, and M. Davidson
Diabetes mellitus in midlife and the risk of dementia three decades later
Neurology, November 23, 2004; 63(10): 1902 - 1907.
[Abstract] [Full Text] [PDF]

A. S. Khachaturian, C. D. Corcoran, L. S. Mayer, P. P. Zandi, and J. C. S. Breitner
Apolipoprotein E {epsilon}4 Count Affects Age at Onset of Alzheimer Disease, but Not Lifetime Susceptibility: The Cache County Study
Arch Gen Psychiatry, May 1, 2004; 61(5): 518 - 524.
[Abstract] [Full Text] [PDF]

P. P. Zandi, J. C. Anthony, A. S. Khachaturian, S. V. Stone, D. Gustafson, J. T. Tschanz, M. C. Norton, K. A. Welsh-Bohmer, and J. C. S. Breitner
Reduced Risk of Alzheimer Disease in Users of Antioxidant Vitamin Supplements: The Cache County Study
Arch Neurol, January 1, 2004; 61(1): 82 - 88.
[Abstract] [Full Text] [PDF]

M. Steinberg, J.-M. Sheppard, J. T. Tschanz, M. C. Norton, D. C. Steffens, J. C.S. Breitner, and C. G. Lyketsos
The Incidence of Mental and Behavioral Disturbances in Dementia: The Cache County Study
J Neuropsychiatry Clin Neurosci, August 1, 2003; 15(3): 340 - 345.
[Abstract] [Full Text] [PDF]

I. Leroi, A. Voulgari, J. C.S. Breitner, and C. G. Lyketsos
The Epidemiology of Psychosis in Dementia
Am J Geriatr Psychiatry, February 1, 2003; 11(1): 83 - 91.
[Abstract] [Full Text] [PDF]

J. M. Silverman, C. J. Smith, D. B. Marin, R. C. Mohs, and C. B. Propper
Familial Patterns of Risk in Very Late-Onset Alzheimer Disease
Arch Gen Psychiatry, February 1, 2003; 60(2): 190 - 197.
[Abstract] [Full Text] [PDF]

P. P. Zandi, M. C. Carlson, B. L. Plassman, K. A. Welsh-Bohmer, L. S. Mayer, D. C. Steffens, J. C. S. Breitner, and for the Cache County Memory Study Investigators
Hormone Replacement Therapy and Incidence of Alzheimer Disease in Older Women: The Cache County Study
JAMA, November 6, 2002; 288(17): 2123 - 2129.
[Abstract] [Full Text] [PDF]

P. P. Zandi, J. C. Anthony, K. M. Hayden, K. Mehta, L. Mayer, and J. C.S. Breitner
Reduced incidence of AD with NSAID but not H2 receptor antagonists: The Cache County Study
Neurology, September 24, 2002; 59(6): 880 - 886.
[Abstract] [Full Text] [PDF]

R. A. Miech, J. C.S. Breitner, P. P. Zandi, A. S. Khachaturian, J. C. Anthony, and L. Mayer
Incidence of AD may decline in the early 90s for men, later for women: The Cache County study
Neurology, January 22, 2002; 58(2): 209 - 218.
[Abstract] [Full Text] [PDF]

R. C. Green, L. A. Cupples, R. Go, K. S. Benke, T. Edeki, P. A. Griffith, M. Williams, Y. Hipps, N. Graff-Radford, D. Bachman, et al.
Risk of Dementia Among White and African American Relatives of Patients With Alzheimer Disease
JAMA, January 16, 2002; 287(3): 329 - 336.
[Abstract] [Full Text] [PDF]

R. A. Watkins, R. Guariglia, J. A. Kaye, and J. S. Janowsky
Informants' Knowledge of Reproductive History and Estrogen Replacement
J. Gerontol. A Biol. Sci. Med. Sci., March 1, 2001; 56(3): 176M - 179.
[Abstract] [Full Text]

R. Heun, A. Papassotiropoulos, F. Jessen, W. Maier, and J. C. S. Breitner
A Family Study of Alzheimer Disease and Early- and Late-Onset Depression in Elderly Patients
Arch Gen Psychiatry, February 1, 2001; 58(2): 190 - 196.
[Abstract] [Full Text] [PDF]

B. L. Plassman, R. J. Havlik, D. C. Steffens, M. J. Helms, T. N. Newman, D. Drosdick, C. Phillips, B. A. Gau, K. A. Welsh-Bohmer, J. R. Burke, et al.
Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias
Neurology, October 24, 2000; 55(8): 1158 - 1166.
[Abstract] [Full Text] [PDF]

J. C. Anthony, J. C. S. Breitner, P. P. Zandi, M. R. Meyer, I. Jurasova, M. C. Norton, and S. V. Stone
Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: The Cache County Study
Neurology, June 13, 2000; 54(11): 2066 - 2071.
[Abstract] [Full Text] [PDF]

C. Kawas, S. Gray, R. Brookmeyer, J. Fozard, and A. Zonderman
Age-specific incidence rates of Alzheimer's disease: The Baltimore Longitudinal Study of Aging
Neurology, June 13, 2000; 54(11): 2072 - 2077.
[Abstract] [Full Text] [PDF]

J. T. Tschanz, K. A. Welsh-Bohmer, I. Skoog, N. West, M. C. Norton, B. W. Wyse, R. Nickles, and J. C. S. Breitner
Dementia diagnoses from clinical and neuropsychological data compared: The Cache County study
Neurology, March 28, 2000; 54(6): 1290 - 1296.
[Abstract] [Full Text] [PDF]

D. C. Steffens, B. L. Plassman, M. J. Helms, K. A. Welsh-Bohmer, T. T. Newman, and J. C. S. Breitner
APOE and AD concordance in twin pairs as predictors of AD in first-degree relatives
Neurology, February 8, 2000; 54(3): 593 - 593.
[Abstract] [Full Text] [PDF]

M. Nicolaou, A. L. DeStefano, I. Gavras, L. A. Cupples, A. J. Manolis, C. T. Baldwin, H. Gavras, and L. A. Farrer
Genetic Predisposition to Stroke in Relatives of Hypertensives
Stroke, February 1, 2000; 31(2): 487 - 492.
[Abstract] [Full Text] [PDF]

J. C. S. Breitner, B. W. Wyse, J. C. Anthony, K. A. Welsh-Bohmer, D. C. Steffens, M. C. Norton, J. T. Tschanz, B. L. Plassman, M. R. Meyer, I. Skoog, et al.
APOE-{epsilon}4 count predicts age when prevalence of AD increases, then declines: The Cache County Study
Neurology, July 1, 1999; 53(2): 321 - 321.
[Abstract] [Full Text] [PDF]

C. H. van Dyck, J. Gelernter, M. G. MacAvoy, R. A. Avery, M. Criden, O. Okereke, P. Varma, J. P. Seibyl, and P. B. Hoffer
Absence of an Apolipoprotein E {epsilon}4 Allele Is Associated With Increased Parietal Regional Cerebral Blood Flow Asymmetry in Alzheimer Disease
Arch Neurol, November 1, 1998; 55(11): 1460 - 1466.
[Abstract] [Full Text] [PDF]

R. J. Ellis, K. Jan, C. Kawas, W. C. Koller, K. E. Lyons, D. V. Jeste, L. A. Hansen, and L. J. Thal
Diagnostic Validity of the Dementia Questionnaire for Alzheimer Disease
Arch Neurol, March 1, 1998; 55(3): 360 - 365.
[Abstract] [Full Text] [PDF]

G. Zubenko, M Wusylko, B. Cohen, F Boller, and I Teply
Family study of platelet membrane fluidity in Alzheimer's disease
Science, October 23, 1987; 238(4826): 539 - 542.
[Abstract] [PDF]

Get information about faster international access.