Am J Psychiatry 1986; 143:1238-1244
Copyright © 1986 by American Psychiatric Association
Two-year longitudinal study of post-stroke mood disorders: comparison of acute-onset with delayed-onset depression
RG Robinson, JR Lipsey, K Rao and TR Price
Patients who developed post-stroke depression 3 to 24 months after hospital
discharge (N = 21) were compared with patients who developed depression
during hospitalization (N = 26) and patients who never developed depression
over 24 months of follow-up (N = 15). During the acute hospitalization and
at follow-up, the three groups were not significantly different in their
demographic characteristics, neurological impairment, intellectual
impairment, or quality of social support. The acute depression group,
however, showed an increased correlation between impairment and depression
from hospitalization to follow-up. Findings suggest that impairment does
not produce depression, but, once depression occurs, it may interact with
impairment to influence post-stroke recovery.