Am J Psychiatry 1986; 143:85-87
Copyright © 1986 by American Psychiatric Association
Combination alprazolam-neuroleptic treatment of the positive and negative symptoms of schizophrenia
OM Wolkowitz, D Pickar, AR Doran, A Breier, J Tarell and SM Paul
Alprazolam, when added under double-blind conditions to a stable
neuroleptic regimen in two patients with schizophrenia, resulted in
clinically apparent improvement in positive and negative schizophrenic
symptoms. Both patients showed significant worsening of symptoms following
reduction or discontinuation of alprazolam.