Metoprolol for intermittent explosive disorder



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	Articles by Mattes, J. A.

Am J Psychiatry 1985; 142:1108-1109
Copyright © 1985 by American Psychiatric Association

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Metoprolol for intermittent explosive disorder

JA Mattes

Metoprolol, a selective beta 1-adrenoreceptor blocker, was administered to two patients with intermittent explosive disorder who had not done well with previous medications, including propranolol and carbamazepine. Both patients improved dramatically, suggesting clinical and theoretical relevance.

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