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Am J Psychiatry 1985; 142:1106-1107
Copyright © 1985 by American Psychiatric Association

REGULAR ARTICLES

Effect of methadone plus neuroleptics on treatment-resistant chronic paranoid schizophrenia

DA Brizer, N Hartman, J Sweeney and RB Millman

In a placebo-controlled single-crossover study, seven patients with treatment-resistant chronic paranoid schizophrenia who received methadone plus neuroleptic showed significant improvement. Methadone may be a useful adjunctive treatment in a subpopulation of patients with chronic paranoid schizophrenia.




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