Am J Psychiatry 1985; 142:866-868
Copyright © 1985 by American Psychiatric Association
Plasma 10-hydroxynortriptyline and ECG changes in elderly depressed patients
RC Young, GS Alexopoulos, CA Shamoian, E Kent, AK Dhar and H Kutt
Among 18 elderly depressed patients given ECGs before and during
nortriptyline treatment, plasma E-10-hydroxynortriptyline and the sum of
E-10-hydroxynortriptyline and nortriptyline distinguished the group with
conduction/repolarization effects. Plasma nortriptyline, age, drug dose,
and baseline cardiovascular status did not.
