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Am J Psychiatry 1985; 142:547-552
Copyright © 1985 by American Psychiatric Association
A controlled study of methylphenidate in the treatment of attention deficit disorder, residual type, in adults
PH Wender, FW Reimherr, D Wood and M Ward
Thirty-seven adult patients meeting the Utah criteria for attention deficit
disorder, residual type, were entered into a double-blind crossover trial
of methylphenidate and placebo. A moderate-to-marked therapeutic response
occurred in 21 (57%) of the patients while receiving methylphenidate and in
four (11%) while receiving placebo, a highly significant difference
statistically and clinically. The responding patients showed significant
improvement in the following areas: attentional difficulty, motor
overactivity, affective lability, and impulsivity. The diagnosis of
attention deficit disorder, residual type, should be considered in patients
with prominent complaints of impulsivity, restlessness, emotional lability,
and hot temper who do not suffer from schizophrenia or major mood disorder
and do not have symptoms of schizotypal or borderline personality
disorders.
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