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Am J Psychiatry 1985; 142:491-492
Copyright © 1985 by American Psychiatric Association

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Toxic reactions to the combination of monoamine oxidase inhibitors and tryptophan

HG Pope Jr, JM Jonas, JI Hudson and MP Kafka

The combination of monoamine oxidase inhibitors and tryptophan--a recognized antidepressant regimen--has been reported to cause behavioral or neurologic toxicity. The authors present eight cases of delirious syndromes apparently attributable to this combination of agents.




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