Am J Psychiatry 1985; 142:441-446
Copyright © 1985 by American Psychiatric Association
Fibromyalgia and major affective disorder: a controlled phenomenology and family history study
JI Hudson, MS Hudson, LF Pliner, DL Goldenberg and HG Pope Jr
Fibromyalgia is a form of nonarticular rheumatism characterized by diffuse
musculoskeletal pain. To investigate the relationship between fibromyalgia
and major affective disorder, the authors evaluated 31 patients with
fibromyalgia and 14 patients with rheumatoid arthritis for rates of current
or past major affective disorder and family history of major affective
disorder. Both the rate of major affective disorder and the familial
prevalence of major affective disorder were significantly higher in the
fibromyalgia patients than the rheumatoid arthritis patients. The results
suggest that fibromyalgia may be related to major affective disorder.
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