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Am J Psychiatry 1985; 142:170-174
Copyright © 1985 by American Psychiatric Association


REGULAR ARTICLES

The time course of information-processing deficits in schizophrenia

DL Braff and DP Saccuzzo

A visual backward masking task was used to specify the time course of the information-processing dysfunction in 19 schizophrenic patients and 15 matched control patients using novel interstimulus intervals. The authors found that the information-processing deficit in schizophrenic subjects occurred at interstimulus intervals of greater than 60 msec and less than 500 msec. These data are compared with the results of evoked-potential and other psychophysiological studies. The visual- processing impairment is specific and time-linked rather than a reflection of the effects of gross psychopathology or medication in schizophrenic individuals.


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