Am J Psychiatry 1985; 142:74-77
Copyright © 1985 by American Psychiatric Association
Concordance for the syndrome of autism in 40 pairs of afflicted twins
ER Ritvo, BJ Freeman, A Mason-Brothers, A Mo and AM Ritvo
The UCLA Registry for Genetic Studies in Autism was established in 1980 to
test the hypothesis that genetic factors may be etiologically significant
in subsets of patients. To date 61 pairs of twins have enrolled and 40 meet
research diagnostic criteria for autism. The authors found a concordance
for autism in these 40 pairs of 95.7% in the monozygotic twins (22 of 23)
and 23.5% in the dizygotic twins (four of 17).
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