Am J Psychiatry 1984; 141:993-995
Copyright © 1984 by American Psychiatric Association
Response to opioids in three patients with restless legs syndrome
PT Trzepacz, EJ Violette and MJ Sateia
Three patients with restless legs syndrome, two of whom also had nocturnal
myoclonus, responded well to treatment with low doses of opioids. The
pathophysiology of the syndrome and the mechanism of opioids' therapeutic
action are discussed.