Am J Psychiatry 1984; 141:692-693
Copyright © 1984 by American Psychiatric Association
Dyskinesia and psychosis in a patient following baclofen withdrawal
V Kirubakaran, D Mayfield and S Rengachary
A paraplegic man with no history of psychiatric illness developed psychosis
and dyskinesia following abrupt withdrawal of baclofen; the symptoms
resolved 72 hours after resumption of the drug. The psychosis and
dyskinesia may have been a manifestation of baclofen's alteration of
cerebral dopaminergic mechanisms.