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Am J Psychiatry 1984; 141:1617-1618
Copyright © 1984 by American Psychiatric Association

REGULAR ARTICLES

Clonidine in the treatment of mania and mixed bipolar disorder

GS Zubenko, BM Cohen, JF Lipinski Jr and JM Jonas

The symptoms of three bipolar patients remitted after clonidine treatment. One patient presented with mixed bipolar disorder, two were manic, and all were psychotic. One patient's akathisia also appeared to respond to clonidine. Clonidine's thymoleptic effect paralleled resulting cardiovascular changes.




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