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Am J Psychiatry 1984; 141:1419-1422
Copyright © 1984 by American Psychiatric Association


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Clinical findings in patients with anorexia nervosa and affective illness in their relatives

ES Gershon, JL Schreiber, JR Hamovit, ED Dibble, W Kaye, JI Nurnberger Jr, AE Andersen and M Ebert

The most prevalent psychiatric disorders in the families of patients with anorexia nervosa are bipolar and unipolar major affective disorder. The presence of affective disorder, self-induced vomiting, or bulimia in the patient is not predictive of affective illness in the relatives. Thus these features do not define genetic heterogeneity within anorexia nervosa. There may be genetic factors shared between anorexia nervosa and affective disorders.


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