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Am J Psychiatry 1984; 141:1271-1273
Copyright © 1984 by American Psychiatric Association


REGULAR ARTICLES

Preliminary results of guanfacine treatment of acute opiate withdrawal

H Schubert, WW Fleischhacker, U Meise and C Theohar

Ten patients experiencing sudden opiate withdrawal received low doses of guanfacine. Improvement was noticeable within the first 4 days and was most evident in moderate to severe cases. The major effect was on autonomic symptoms. Tolerance to guanfacine was excellent.


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Neurobiological Adaptations to Psychostimulants and Opiates as a Basis of Treatment Development
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