Fast-cycling bipolar disorder induced by withdrawal from long-term treatment with a tricyclic antidepressant



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Am J Psychiatry 1984; 141:108-109
Copyright © 1984 by American Psychiatric Association

REGULAR ARTICLES

Fast-cycling bipolar disorder induced by withdrawal from long-term treatment with a tricyclic antidepressant

BD Jones, S Steinberg and G Chouinard

A unipolar depressed patient developed a fast-cycling bipolar disorder on abrupt discontinuation of long-term treatment with a tricyclic antidepressant. The case illustrates the potential for drug withdrawal to induce mood disturbance that is more severe than the original illness.

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