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Am J Psychiatry 1983; 140:456-458
Copyright © 1983 by American Psychiatric Association

BRIEF REPORTS

L-5-hydroxytryptophan for LSD-induced psychosis

HD Abraham

The serotonin precursor L-5-hydroxytryptophan reversed the symptoms of a 23-year-old man suffering from LSD-induced psychosis who participated in a randomized, double-blind crossover study of the drug and a placebo. This finding is compatible with the speculation that some LSD- induced psychotic disorders may be caused by a relative deficiency of CNS serotonin.




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