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Am J Psychiatry 1982; 139:1102-1113
Copyright © 1982 by American Psychiatric Association


SPECIAL ARTICLES

Psychotherapy and pharmacotherapy: toward an integrative model

TB Karasu

The author reviews historical trends, hypotheses, and problems in the application of pharmacotherapy and psychotherapy and uses research findings to develop an integrative model. He portrays a chronology of models over three decades; an "additive" relationship represents the decade of 1970 to 1980. He presents factors that must be considered in determining the effects of pharmacotherapy plus psychotherapy and recommends refinement of these variables in future research.


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