Am J Psychiatry 1982; 139:1057-1058
Copyright © 1982 by American Psychiatric Association
Controlled trial of zimelidine, a 5-HT reuptake inhibitor, for treatment of depression
A Georgotas, M Krakowski and S Gershon
The authors conducted a double-blind, placebo-controlled clinical trial of
the selective 5-HT reuptake inhibitor zimelidine in the treatment of major
depressive illness. Zimelidine had the same antidepressant efficacy as
amitriptyline but significantly fewer side effects, especially
anticholinergic effects.