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Am J Psychiatry 1982; 139:939-941
Copyright © 1982 by American Psychiatric Association


REGULAR ARTICLES

Drug-induced rapid cycling: possible outcomes and management

G Oppenheim

Rapid cycling of mood change induced by antidepressant drugs has recently emerged as a significant diagnostic and therapeutic problem. The author describes two additional cases. Cessation of treatment with the offending drug may leave the patient depressed, manic, or euthymic or in a state of continued rapid cycling. The author suggests an approach to management of this condition.


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