Am J Psychiatry 1982; 139:939-941
Copyright © 1982 by American Psychiatric Association
Drug-induced rapid cycling: possible outcomes and management
G Oppenheim
Rapid cycling of mood change induced by antidepressant drugs has recently
emerged as a significant diagnostic and therapeutic problem. The author
describes two additional cases. Cessation of treatment with the offending
drug may leave the patient depressed, manic, or euthymic or in a state of
continued rapid cycling. The author suggests an approach to management of
this condition.