Am J Psychiatry 1982; 139:92-94
Copyright © 1982 by American Psychiatric Association
Propranolol and depression
WM Petrie, RJ Maffucci and RL Woosley
The authors report the cases of 3 patients who had depressive episodes
after administration of propranolol for medical illnesses. The depressive
episodes were severe, occurred in a dose-dependent manner, and promptly
remitted when propranolol was discontinued. Physicians' awareness of this
complication, especially in cases of patients with a history of depression,
may reduce the occurrence of this drug reaction.