Am J Psychiatry 1981; 138:1626-1627
Copyright © 1981 by American Psychiatric Association
"On-off" syndrome treated with lithium carbonate: a case report
DR Ross, CE Coffey, EL Ferren, JI Walker and CW Olanow
The authors describe a 42-year-old man who developed "on-off" episodes and
for whom lithium carbonate proved an effective treatment. They speculate
that the predominant effect of lithium in the "on-off" syndrome is to
prevent L-dopa desensitization of the dopamine receptor.